Channelpedia

PubMed 1332832


Referenced in: none

Automatically associated channels: Kv10.1



Title: Photoaffinity labeling of the electroplax sodium channel with a photoreactive mu-conotoxin carrying a radioactive and chromogenic diazirine.

Authors: Y Hatanaka, H Nakayama, Y Kanaoka

Journal, date & volume: Chem. Pharm. Bull., 1992 Sep , 40, 2537-9

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/1332832


Abstract
Photoreactive derivatives of mu-conotoxin GIIIA carrying a radioactive and chromogenic diazirine have been prepared as a photoaffinity labeling reagent for muscle-type sodium channels. When the reagent was photolyzed in the presence of the eel sodium channel, radioactivity was specifically incorporated into the channel protein.