Referenced in: none

Automatically associated channels: Kv10.1

Title: Redesignation of a purported P1.15 subtype-specific meningococcal monoclonal antibody as a P1.19-specific reagent.

Authors: E Wedege, D A Caugant, A Musacchio, N B Saunders, W D Zollinger

Journal, date & volume: Clin. Diagn. Lab. Immunol., 1999 Jul , 6, 639-42

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/10391880

Abstract
Two reference monoclonal antibodies against the meningococcal P1.15 subtype PorA, MN3C5C and 2-1-P1.15, showed only partial concordant recognition of meningococcal isolates. Cyanogen bromide cleavage of P1.19,15 PorA, peptide mapping, and sequencing of porA regions demonstrated that 2-1-P1.15 was specific for subtype P1.19, and henceforth it is to be redesignated as 2-1-P1.19.