Referenced in: none

Automatically associated channels: Kir2.3

Title: [Effect of endogenous nitric oxide on the nerve-muscle synapse function]

Authors: A L Zefirov, R R Khaliullina, A A Anuchin, A V Iakovlev

Journal, date & volume: , 2001 Apr , 87, 499-506

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/11449977

Abstract
The nitric oxide (NO) precursor L-arginine was found to decrease the amplitude and the quantum content of the EPPs and to increase the amplitude of the AP third deflection in the frog neuromuscular junction of the m. cutaneous pectoris preparation. Inhibitor of the NO synthase NG-nitro-L-arginine methylester exerted opposite effects. The data obtained suggest that endogenous NO is produced in the neuromuscular synapse area and can modify the work of potassium ion channels.