Referenced in: none

Automatically associated channels: Kir2.3

Title: Lambert-Eaton myasthenic syndrome: electrodiagnostic findings and response to treatment.

Authors: R W Tim, J M Massey, D B Sanders

Journal, date & volume: Neurology, 2000 Jun 13 , 54, 2176-8

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/10851390

Abstract
The authors reviewed the incidence of cancer, repetitive nerve stimulation findings, and response to treatment in 73 patients with Lambert-Eaton myasthenic syndrome. Thirty-one patients (42%) had lung cancer, 29 small cell. Doubling of the compound motor action potential amplitude in three tested distal muscles was seen in only 41% of patients. Treatment with 3, 4-diaminopyridine produced moderate to marked self-reported functional improvement in 79% of the 53 treated patients.