Referenced in: none

Automatically associated channels: Kir6.2

Title: [The role of chloride channels and chloride ions in steroidogenesis regulation in the gonads of amphibians, birds and mammals]

Authors: M N Skoblina

Journal, date & volume: Ontogenez, 2002 Jul-Aug , 33, 292-302

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/12174575

Abstract
The paper represents the first review of data on the involvement of chloride channels (their inhibitors and media, in which chloride ions are substituted for anions that poorly penetrate in the cell) in the regulation of basal and gonadotropin-stimulated steroidogenesis in the gonads of amphibians, birds, and mammals. Possible causes are considered for different reactions of the gonad steroidogenic cells in representatives of different vertebrate classes to a decreased medium concentration of chloride and the involvement of chloride channels and/or chloride ions in the regulation of steroidogenesis is discussed.