Referenced in: none

Automatically associated channels: Kv11.1

Title: Optimization of a tertiary alcohol series of phosphodiesterase-4 (PDE4) inhibitors: structure-activity relationship related to PDE4 inhibition and human ether-a-go-go related gene potassium channel binding affinity.

Authors: Richard W Friesen, Yves Ducharme, Richard G Ball, Marc Blouin, Louise Boulet, Bernard Côté, Richard Frenette, Mario Girard, Daniel Guay, Zheng Huang, Thomas R Jones, France Laliberté, Joseph J Lynch, Joseph Mancini, Evelyn Martins, Paul Masson, Eric Muise, Douglas J Pon, Peter K S Siegl, Angela Styhler, Nancy N Tsou, Mervyn J Turner, Robert N Young, Yves Girard

Journal, date & volume: J. Med. Chem., 2003 Jun 5 , 46, 2413-26

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/12773045

Abstract