Referenced in: none

Automatically associated channels: TRP , TRPV , TRPV1

Title: TRPV1: Turning up the heat on intestinal tumorigenesis.

Authors: Petrus R de Jong, Samuel Bertin, Eyal Raz

Journal, date & volume: Mol Cell Oncol, 2015 Jan-Mar , 2, e975619

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/27308393

Abstract
TRP channels are associated with the development and progression of cancer but their precise molecular roles in these processes are unclear. Recently, we showed that the transient receptor potential cation channel, subfamily V, member 1 (TRPV1) ion channel is part of a negative feedback loop downstream of epidermal growth factor receptor signaling that suppresses intestinal tumorigenesis.