Referenced in: none

Automatically associated channels: Kv11.1

Title: A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.

Authors: Claire Le Manach, Tanya Paquet, Christel Brunschwig, Mathew Njoroge, Ze Han, Diego González Cabrera, Sridevi Bashyam, Rajkumar Dhinakaran, Dale Taylor, Janette Reader, Mariette Botha, Alisje Churchyard, Sonja Lauterbach, Theresa L Coetzer, Lyn-Marie Birkholtz, Stephan Meister, Elizabeth A Winzeler, David Waterson, Michael J Witty, Sergio Wittlin, María-Belén Jiménez-Díaz, María Santos Martínez, Santiago Ferrer, Iñigo Angulo-Barturen, Leslie J Street, Kelly Chibale

Journal, date & volume: J. Med. Chem., 2015 Nov 12 , 58, 8713-22

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/26502160

Abstract