Referenced in: none

Automatically associated channels: TASK1

Title: Transformation of cortical and hippocampal neural circuit by environmental enrichment.

Authors: H Hirase, Y Shinohara

Journal, date & volume: Neuroscience, 2014 Nov 7 , 280, 282-98

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25242640

Abstract
It has been half a century since brain volume enlargement was first reported in animals reared in an enriched environment (EE). As EE animals show improved memory task performance, exposure to EE has been a useful model system for studying the effects of experience on brain plasticity. We review EE-induced neural changes in the cerebral cortex and hippocampus focusing mainly on works published in the recent decade. The review is organized in three large domains of changes: anatomical, electrophysiological, and molecular changes. Finally, we discuss open issues and future outlook toward better understanding of EE-induced neural changes.