Referenced in: none

Automatically associated channels: Kv11.1

Title: Optimization of diarylthiazole B-raf inhibitors: identification of a compound endowed with high oral antitumor activity, mitigated hERG inhibition, and low paradoxical effect.

Authors: Maurizio Pulici, Gabriella Traquandi, Chiara Marchionni, Michele Modugno, Rosita Lupi, Nadia Amboldi, Elena Casale, Nicoletta Colombo, Luca Corti, Marina Fasolini, Fabio Gasparri, Wilma Pastori, Alessandra Scolaro, Daniele Donati, Eduard Felder, Arturo Galvani, Antonella Isacchi, Enrico Pesenti, Marina Ciomei

Journal, date & volume: ChemMedChem, 2015 Feb , 10, 276-95

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25430902

Abstract