Channelpedia

PubMed 25466191


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Nav1 , Nav1.7



Title: Dibenzazepines and dibenzoxazepines as sodium channel blockers.

Authors: Stephen M Lynch, Laykea Tafesse, Kevin Carlin, Parijat Ghatak, Donald J Kyle

Journal, date & volume: Bioorg. Med. Chem. Lett., 2015 Jan 1 , 25, 43-7

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25466191


Abstract
We have identified two related series of dibenzazepine and dibenzoxazepine sodium channel blockers, which showed good potency on Nav1.7 in FLIPR-based and electrophysiological functional assays.