Referenced in: none

Automatically associated channels: ClC2 , ClC3 , ClC4

Title: [Expressions of chloride channel ClC-2 and ClC-3 in human nasal polyps]

Authors: Huabin Li, Demin Han, Bing Zhou, Erzhong Fan, Zhongyan Liu

Journal, date & volume: , 2003 May , 17, 266-7

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/12916350

Abstract
To investigate the role of chloride channel ClC-2 and ClC-3 in human nasal polyps.Two chloride channels ClC-2 and ClC-3 were studied in 27 cases of nasal polyps with immunochemistric staining.Nasal polyps revealed strong positive staining of ClC-2 and ClC-3, the ClC-2 and ClC-3 proteins localized mainly in epithelial cells, sub-epithelial mucous glands without significant distinction. The number of positive cells of ClC-2 and ClC-3 are 17.6 +/- 6.33 and 23.49 +/- 6.14.The chloride channels ClC-2 and ClC-3 may play a role in the formation of nasal polyps.