Referenced in: none

Automatically associated channels: TRP

Title: [Identification of genetic polymorphisms associated with overweight in athletes of winter sports].

Authors: E Iu Sorokina, T N Solntseva, R M Radzhabkadiev, A S Samoĭlov

Journal, date & volume: Vopr Pitan, 2013 , 82, 58-61

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24741957

Abstract
The identification of polymorphisms rs9939609 gene FTO, Trp64Arg ADRB3 and gene -866G> A UCP2 gene using multiplex allele-specific PCR hybridization-fluorescence detection in real time has been carried out in highly skilled athletes under the age of 30 years engaged in biathlon (n = 25) and bobsleigh (n = 28). The data on the frequency of allele risk of obesity has been obtained. The study of polymorphism rs9939609 of the FTO gene in biathletes found that 30% of them are carriers of the risk allele of obesity (A). Among the bobsledder the frequency of allele A is slightly higher than in European populations and is 55.4%. The study of gene polymorphism Trp64Arg ADRB3 shored that the frequency of risk allele of obesity 64Arg in biathletes (14%) was slightly higher than in the European population and biathletes (5.4%). The results of the identification of polymorphism -866G> A gene UCP2 in biathletes and bobsledders, found the incidence of obesity risk allele, respectively, 52 and 58.7%.