Referenced in: none

Automatically associated channels: TRP , TRPP , TRPP1

Title: Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.

Authors: Djalila Mekahli, Jean-Paul Decuypere, Eva Sammels, Kirsten Welkenhuyzen, Joost Schoeber, Marie-Pierre Audrezet, Anniek Corvelyn, Georges Dechenes, Albert C M Ong, Martijn J Wilmer, Lambertus van den Heuvel, Geert Bultynck, Jan B Parys, Ludwig Missiaen, Elena Levtchenko, Humbert De Smedt

Journal, date & volume: Pflugers Arch., 2014 Aug , 466, 1591-604

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24193408

Abstract