Referenced in: none

Automatically associated channels: Kv11.1

Title: Potent N-(1,3-thiazol-2-yl)pyridin-2-amine vascular endothelial growth factor receptor tyrosine kinase inhibitors with excellent pharmacokinetics and low affinity for the hERG ion channel.

Authors: Mark T Bilodeau, Adrienne E Balitza, Timothy J Koester, Peter J Manley, Leonard D Rodman, Carolyn Buser-Doepner, Kathleen E Coll, Christine Fernandes, Jackson B Gibbs, David C Heimbrook, William R Huckle, Nancy Kohl, Joseph J Lynch, Xianzhi Mao, Rosemary C McFall, Debra McLoughlin, Cynthia M Miller-Stein, Keith W Rickert, Laura Sepp-Lorenzino, Jennifer M Shipman, Raju Subramanian, Kenneth A Thomas, Bradley K Wong, Sean Yu, George D Hartman

Journal, date & volume: J. Med. Chem., 2004 Dec 2 , 47, 6363-72

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/15566305

Abstract