Referenced in: none

Automatically associated channels: Kv11.1

Title: Inhibitors of β-site amyloid precursor protein cleaving enzyme (BACE1): identification of (S)-7-(2-fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno[2,3-b]pyridine-5,4'-oxazol]-2'-amine (AMG-8718).

Authors: Thomas A Dineen, Kui Chen, Alan C Cheng, Katayoun Derakhchan, Oleg Epstein, Joel Esmay, Dean Hickman, Chuck E Kreiman, Isaac E Marx, Robert C Wahl, Paul H Wen, Matthew M Weiss, Douglas A Whittington, Stephen Wood, Robert T Fremeau, Ryan D White, Vinod F Patel

Journal, date & volume: J. Med. Chem., 2014 Dec 11 , 57, 9811-31

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/25363711

Abstract