Channelpedia

PubMed 24165728


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Nav1 , Nav1.9



Title: No pain, more gain.

Authors: James J Cox, John N Wood

Journal, date & volume: Nat. Genet., 2013 Nov , 45, 1271-2

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24165728


Abstract
A new study shows that a specific mutation in SCN11A, which encodes the Nav1.9 voltage-gated sodium channel, underlies a human disorder characterized by insensitivity to pain. This finding provides fresh insights into human pain perception and suggests a new avenue for the development of analgesic drugs.