Referenced in: none

Automatically associated channels: Slo1

Title: Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease.

Authors: Paul S Aisen, Jeffrey Cummings, Lon S Schneider

Journal, date & volume: Cold Spring Harb Perspect Med, 2012 Mar , 2, a006395

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22393531

Abstract
In this work we consider marketed drugs for Alzheimer disease (AD) including acetylcholinesterase inhibitors (AChE-Is) and antiglutamatergic treatment involving the N-methyl-d-aspartate (NMDA) receptor. We discuss medications and substances available for use as cognitive enhancers that are not approved for AD or cognitive impairment, and other neurotransmitter-related therapies in development or currently being researched. We also review putative therapies that aim to slow disease progression by mechanisms not directly related to amyloid or tau.