Referenced in: none

Automatically associated channels: Kv11.1

Title: Discovery of 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): a positive allosteric modulator of the metabotropic glutamate 2 receptor.

Authors: Jose María Cid, Gary Tresadern, Juan Antonio Vega, Ana Isabel de Lucas, Encarnación Matesanz, Laura Iturrino, María Lourdes Linares, Aránzazu García, José Ignacio Andrés, Gregor J Macdonald, Daniel Oehlrich, Hilde Lavreysen, Anton Megens, Abdellah Ahnaou, Wilhelmus Drinkenburg, Claire Mackie, Stefan Pype, David Gallacher, Andrés A Trabanco

Journal, date & volume: J. Med. Chem., 2012 Oct 25 , 55, 8770-89

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/23072213

Abstract