Referenced in: none

Automatically associated channels: Kv11.1

Title: Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor.

Authors: Heather J Finlay, John Lloyd, Wayne Vaccaro, Alexander Kover, Lin Yan, Gauri Bhave, Joseph Prol, Tram Huynh, Rao Bhandaru, Yolanda Caringal, John DiMarco, Jinping Gan, Tim Harper, Christine Huang, Mary Lee Conder, Huabin Sun, Paul Levesque, Michael Blanar, Karnail Atwal, Ruth Wexler

Journal, date & volume: J. Med. Chem., 2012 Apr 12 , 55, 3036-48

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22409629

Abstract