PubMed 22498302
Referenced in: none
Automatically associated channels: TRP
Title: Drosophila visual transduction.
Authors: Craig Montell
Journal, date & volume: Trends Neurosci., 2012 Jun , 35, 356-63
PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22498302
Abstract
Visual transduction in the Drosophila compound eye functions through a pathway that couples rhodopsin to phospholipase C (PLC) and the opening of transient receptor potential (TRP) channels. This cascade differs from phototransduction in mammalian rods and cones, but is remarkably similar to signaling in mammalian intrinsically photosensitive retinal ganglion cells (ipRGCs). In this review, I focus on recent advances in the fly visual system, including the discovery of a visual cycle and insights into the machinery and mechanisms involved in generating a light response in photoreceptor cells.