Referenced in: none

Automatically associated channels: TRP , TRPV , TRPV1

Title: Lipids: LPA activates TRPV1--and it hurts.

Authors: Gabor Tigyi

Journal, date & volume: Nat. Chem. Biol., 2012 Jan , 8, 22-3

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22173354

Abstract
Lysophosphatidic acid, a lipid mediator, second messenger and intermediate in lipid biosynthesis, finds a new intracellular target in TRPV1. This nonselective cation channel is also targeted by the analgesic capsaicin, which acts to desensitize the channel