Referenced in: none

Automatically associated channels: Kv11.1

Title: Balancing hERG affinity and absorption in the discovery of AZD5672, an orally active CCR5 antagonist for the treatment of rheumatoid arthritis.

Authors: John G Cumming, Howard Tucker, John Oldfield, Colin Fielding, Adrian Highton, Alan Faull, Martin Wild, Dearg Brown, Stuart Wells, John Shaw

Journal, date & volume: Bioorg. Med. Chem. Lett., 2012 Feb 15 , 22, 1655-9

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/22266038

Abstract