Referenced in: none

Automatically associated channels: TRP , TRPV , TRPV1

Title: Discovery of potent, soluble and orally active TRPV1 antagonists. Structure-activity relationships of a series of isoxazoles.

Authors: Paul Ratcliffe, Lynn Abernethy, Nasrin Ansari, Ken Cameron, Tom Clarkson, Maureen Dempster, David Dunn, Anna-Marie Easson, Darren Edwards, Katy Everett, Helen Feilden, Koc-Kan Ho, Steve Kultgen, Peter Littlewood, John Maclean, Duncan McArthur, Deborah McGregor, Hazel McLuskey, Irina Neagu, Olaf Nimz, Lesley-Anne Nisbet, Michael Ohlmeyer, Ronnie Palin, Quynhchi Pham, Yajing Rong, Andrew Roughton, Melanie Sammons, Robert Swanson, Heather Tracey, Glenn Walker

Journal, date & volume: Bioorg. Med. Chem. Lett., 2011 Aug 1 , 21, 4652-7

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/21723725

Abstract