PubMed 21056492

Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Kir1.1 , Kir6.2

Title: Successful sulfonylurea treatment of a neonate with neonatal diabetes mellitus due to a new KCNJ11 mutation.

Authors: Miloš M Ješić, Maja D Ješić, Svjetlana Maglajlić, Silvija Sajić, Svetislav Necić

Journal, date & volume: Diabetes Res. Clin. Pract., 2011 Jan , 91, e1-3

PubMed link:

Mutations in the KCNJ11 gene, which encodes the Kir6.2 subunit of the ATP-sensitive potassium channel, often result in neonatal diabetes. We describe a female neonate who is a heterozygous for a new missense mutation, V252L, in the KCNJ11 gene and who has been successfully transitioned from insulin to sulfonylurea therapy.