Referenced in: none

Automatically associated channels: Slo1

Title: The plant vacuole: Emitter and receiver of calcium signals.

Authors: Edgar Peiter

Journal, date & volume: , 2011 Mar 2 , ,

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/21376393

Abstract
This review portrays the plant vacuole as both a source and a target of Ca(2+) signals. In plants, the vacuole represents a Ca(2+) store of enormous size and capacity. Total and free Ca(2+) concentrations in the vacuole vary with plant species, cell type, and environment, which is likely to have an impact on vacuolar function and the release of vacuolar Ca(2+). It is known that cytosolic Ca(2+) signals are often generated by release of the ion from internal stores, but in very few cases has a role of the vacuole been directly demonstrated. Biochemical and electrophysical studies have provided evidence for the operation of ligand- and voltage-gated Ca(2+)-permeable channels in the vacuolar membrane. The underlying molecular mechanisms are largely unknown with one exception: the slow vacuolar channel, encoded by TPC1, is the only vacuolar Ca(2+)-permeable channel cloned to date. However, due to its complex regulation and its low selectivity amongst cations, the role of this channel in Ca(2+) signalling is still debated. Many transport proteins at the vacuolar membrane are also targets of Ca(2+) signals, both by direct binding of Ca(2+) and by Ca(2+)-dependent phosphorylation. This enables the operation of feedback mechanisms and integrates vacuolar transport systems in the wider signalling network of the plant cell.