Referenced in: none

Automatically associated channels: Kv11.1

Title: Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicity.

Authors: George Papadatos, Muhammad Alkarouri, Valerie J Gillet, Peter Willett, Visakan Kadirkamanathan, Christopher N Luscombe, Gianpaolo Bravi, Nicola J Richmond, Stephen D Pickett, Jameed Hussain, John M Pritchard, Anthony W J Cooper, Simon J F Macdonald

Journal, date & volume: J Chem Inf Model, 2010 Oct 25 , 50, 1872-86

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/20873842

Abstract