Referenced in: none

Automatically associated channels: Kir2.3

Title: Distribution of GABA receptors in the rat cerebellum.

Authors: A E Kingsbury, G P Wilkin, A J Patel, R Balázs

Journal, date & volume: J. Neurochem., 1980 Sep , 35, 739-42

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/6256496

Abstract
The distribution of GABA receptors in the cerebellum is not homogeneous. In comparison with detergent-treated membranes from the whole tissue the number of [3H]muscimol binding sites per mg protein (Bmax) is about doubled in preparations enriched in large fragments of the cerebellar glomeruli, and it is about one-third in the dissected deep nuclei. On the other hand, the apparent affinity (Kd) is similar in the different preparations. Comparison of the results with earlier studies suggests a heterogeneity in cerebellar GABA receptors and/or their control.