Referenced in: none

Automatically associated channels: Kir6.2

Title: Regional ontogenetic profile of central and peripheral benzodiazepine receptors in the guinea pig brain.

Authors: J L Daval, J Deckert, T Nakajima, P F Morgan, P J Marangos

Journal, date & volume: Neurosci. Lett., 1988 Sep 23 , 92, 82-5

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/2847091

Abstract
The ontogenetic development of 'central' and 'peripheral' benzodiazepine (BZ) receptors was investigated in 3 different regions of the guinea pig brain. A marked difference in the developmental profile of these two types of binding sites was observed. The density of central-type receptors gradually increased during embryonic life (especially in cortex and cerebellum), without major changes after birth, while the reverse was true for peripheral-type binding sites. These data contrast with those previously reported in rat, suggesting species differences.