Channelpedia

PubMed 1337929


Referenced in: none

Automatically associated channels: Kir2.3 , Kir6.2



Title: Postnatal ontogenesis of neurons containing GABAA alpha 1 subunit mRNA in the rat forebrain.

Authors: J H Zhang, M Sato, T Araki, M Tohyama

Journal, date & volume: Brain Res. Mol. Brain Res., 1992 Dec , 16, 193-203

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/1337929


Abstract
The expression of GABAA receptor alpha 1 subunit mRNA in the postnatal rat forebrain was examined by in situ hybridization histochemistry. In most regions, including the isocortex, olfactory bulb, amygdala, septum, nucleus of the diagonal band, bed nucleus of the stria terminalis, basal ganglia, thalamus, and hypothalamus, the expression of alpha 1 subunit mRNA was low at birth but showed a dramatic increase during the early postnatal period. Adult levels of expression were reached at around the second or third week of life in these regions. However, in the caudate-putamen, and the nucleus accumbens, the expression of this subunit was only transient.