Referenced in: none

Automatically associated channels: Kir2.3

Title: Identification of serovar-specific single-nucleotide polymorphisms of C. Trachomatis omp1 gene.

Authors: V I Sharkeev, I Y Torshin, M M Shkarupeta, T A Akopian, V N Lazarev, V M Govorun

Journal, date & volume: Bull. Exp. Biol. Med., 2005 Aug , 140, 222-7

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/16283007

Abstract
Complete sequences of omp1 gene encoding chlamydial main outer membrane protein were analyzed in 76 clinical strains of C. trachomatis. Thirty-four serovar-specific single-nucleotide polymorphisms were identified, 20 of them meet two criteria: unique position of the nucleotide and unique nucleotide substitution. Evaluation of serovar-specific single-nucleotide polymorphisms of omp1 gene can appreciably simplify and accelerate genetic diagnosis of C. trachomatis serovars.