Referenced in: none

Automatically associated channels: Kir2.3

Title: [The tuning of striate neurons to cross-like figures during local blockade of intracortical inhibition].

Authors: I A Shevelev, U T Eysel, K U Jirmann, G A Sharaev

Journal, date & volume: Zh Vyssh Nerv Deiat Im I P Pavlova, 1999 Mar-Apr , 49, 271-8

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/10486896

Abstract
Many neurons in the cat primary visual cortex reveal sensitivity to cruciform and corner figures as well as to local orientation discontinuities. We investigated this sensitivity in 85 V1 neurons before and after the local blockade of GABA(A)ergic inhibition by microiontophoretic application of bicuculline and observed two opposite effects: a decrease or disappearance of sensitivity to crosses in about half of the neurons and its increase or appearance in about one third of the units. The results indicate substantial and drastically different contribution of intracortical inhibition to sensitivity to line-crossings in the visual cortical neurons. Some possible mechanisms of this difference are discussed.