PubMed 17521564
Referenced in: none
Automatically associated channels: Kir2.3
Title: The sodium "leak" has finally been plugged.
Authors: Terrance P Snutch, Arnaud Monteil
Journal, date & volume: Neuron, 2007 May 24 , 54, 505-7
PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/17521564
Abstract
Most electrophysiologists generally do not speak highly of leak currents. In reality, these conductances represent a crucial functional mechanism by which neurons control resting membrane potentials. A new study in Cell by Lu et al. has surprisingly confirmed the identity of the long-sought voltage-insensitive sodium leak conductance to be encoded by the third branch of the voltage-gated sodium and calcium channel family.