Referenced in: none

Automatically associated channels: Kir2.3

Title: [Varenicline--a new drug for smoking cessation].

Authors: Philip Tønnesen

Journal, date & volume: Ugeskr. Laeg., 2007 Nov 19 , 169, 4051-2

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/18078657

Abstract
Varenicline is a new drug for smoking cessation that reduces cravings by binding to the alfa4-beta2-nicotine-achethylcholine receptors in the brain (partial agonist). Varenicline for 12 weeks was found to be effective for smoking cessation and more effective than bupropionSR after 3 months. The adverse events were mild with transient nausea reported by less than one third of the subjects. Varenicline should be used for smoking cessation when nicotine replacement products have failed or are undesired.