Channelpedia

PubMed 11719196


Referenced in: none

Automatically associated channels: Kv10.1



Title: Potassium channel mechanics.

Authors: F J Sigworth

Journal, date & volume: Neuron, 2001 Nov 20 , 32, 555-6

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/11719196


Abstract
What is the moving part that switches an ion channel's current on and off? In this issue of Neuron del Camino and Yellen (2001) exploit scanning cysteine mutagenesis and sulfhydryl reagents to show that the intracellular end of the S6 helices forms a mechanical gate for the Shaker potassium channel.