Channelpedia

PubMed 15473959


Referenced in: none

Automatically associated channels: Kir6.2



Title: Peering into the birth canal during ion channel parturition.

Authors: James S Trimmer

Journal, date & volume: Neuron, 2004 Oct 14 , 44, 214-6

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/15473959


Abstract
Recent studies have provided detailed structures of the N-terminal T1 domain of Kv channel alpha subunits that mediates contranslational subunit assembly. In this issue of Neuron, Kosolapov et al. probe T1 domain structure within the ribosomal tunnel. They find that the T1 domain forms secondary structure within the tunnel, in preparation for its immediate role in governing channel assembly upon exit.