Referenced in: none

Automatically associated channels: Kv10.1

Title: Redoxing calcium from the ER.

Authors: H Llewelyn Roderick, Martin D Bootman

Journal, date & volume: Cell, 2005 Jan 14 , 120, 4-5

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/15652474

Abstract
Inositol 1,4,5-trisphosphate (InsP(3))-induced calcium release from the endoplasmic reticulum (ER) intracellular calcium store regulates cellular functions from the beginning of life at fertilization until death. In this issue of Cell, Mikoshiba and colleagues describe a novel mode of regulation of the InsP(3) receptor (InsP(3)R) governed by ER luminal redox status, calcium, and pH .