Channelpedia

PubMed 2462662


Referenced in: none

Automatically associated channels: Kv10.1



Title: Sodium influxes in renal epithelial LLC-PK1/Cl4 cells monitored by 23Na NMR.

Authors: A W Jans, R Willem, E R Kellenbach, R K Kinne

Journal, date & volume: , 1988 Jul , 7, 292-9

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/2462662


Abstract
23Na NMR experiments with a suspension of the renal epithelial cell line, LLC-PK1/Cl4, in the presence of the shift reagent dysprosium polyphosphate showed that the intracellular sodium was only NMR visible for 64 +/- 4%. Intracellular sodium content was found to be 30.6 +/- 1.2 mM (25 degrees C). Examination of the sodium influx during recovery from intracellular acidification showed that sodium is transported not only by Na+/H+ exchange but also by sodium-D-glucose cotransport with a stoichiometry of 1:1.