Referenced in: none

Automatically associated channels: Kir6.2

Title: Simultaneous measurements of ionic currents, tension and optical properties of voltage clamped skeletal muscle fibres.

Authors: J Poledna, L Lacinova

Journal, date & volume: Gen. Physiol. Biophys., 1988 Feb , 7, 17-28

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/2456248

Abstract
The paper presents the voltage clamp method for isolated skeletal muscle cells, which allows simultaneous measurements of ionic currents, tension and changes in their optical properties. Experimental results illustrate the range of possible applications. Measurements with two types of preparations, frog and crayfish, exhibiting differences in EC coupling are compared. Basic characteristics of the voltage dependence of tension and birefringence during activation of contraction are described.