Referenced in: none

Automatically associated channels: Kir6.2

Title: Rapid postnatal changes in F1-ATPase proteins and in the uncoupling protein in brown adipose tissue mitochondria of the newborn rat.

Authors: A M Luis, J M Cuezva

Journal, date & volume: Biochem. Biophys. Res. Commun., 1989 Feb 28 , 159, 216-22

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/2522301

Abstract
Changes in F1-ATPase and UCP protein contents and in the activity of respiratory complexes I, II and IV of brown adipose tissue mitochondria are reported during the first 0-6 hours of life in the rat. Mitochondrial UCP/F1-ATPase protein ratio is used to define the onset of thermogenic differentiation of brown adipose tissue mitochondria. It is concluded that mitochondrial differentiation occurs soon after birth and that the process is accelerated by hypothermic conditions.