Referenced in: none

Automatically associated channels: Kv10.1 , Slo1

Title: Alteration of four identified K+ currents in Drosophila muscle by mutations in eag.

Authors: Y Zhong, C F Wu

Journal, date & volume: Science, 1991 Jun 14 , 252, 1562-4

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/2047864

Abstract
Voltage-clamp analysis of Drosophila larval muscle revealed that ether à go-go (eag) mutations affected all identified potassium currents, including those specifically eliminated by mutations in the Shaker or slowpoke gene. Together with DNA sequence analysis, the results suggest that the eag locus encodes a subunit common to different potassium channels. Thus, combinatorial assembly of polypeptides from different genes may contribute to potassium channel diversity.