Title: Fifteen years of NaV 1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?

Authors: David A Eagles, Chun Yuen Chow, Glenn F King

Journal, date & volume: Br J Pharmacol, 2022Jul, 179, 3592-3611

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/33206998

Abstract