Kir2.1

1

Swale DR et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.
ACS Chem Neurosci, 2016 May 24 , ().

2

Hsieh CP et al. The mechanism of inward rectification in Kir channels: A novel kinetic model with non-equilibrium thermodynamics approach.
Biophys. Chem., 2016 May , 212 (1-8).

3

Ye W et al. The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction.
Proc. Natl. Acad. Sci. U.S.A., 2016 Jan 12 , 113 (E229-38).

4

Adams DS et al. Bioelectric signalling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome.
J. Physiol. (Lond.), 2016 Feb 10 , ().

5

Crumb WJ et al. An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel.
J Pharmacol Toxicol Methods, 2016 Apr 6 , ().

6

Asmar A et al. Membrane channel gene expression in human costal and articular chondrocytes.
Organogenesis, 2016 Apr 2 , 12 (94-107).

7

Touhara KK et al. The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-tetramers.
Elife, 2016 , 5 ().

8

Siddiqui TA et al. Complex molecular and functional outcomes of single versus sequential cytokine stimulation of rat microglia.
J Neuroinflammation, 2016 , 13 (66).

9

Climent AM et al. The Role of Atrial Tissue Remodeling on Rotor Dynamics: An In-Vitro Study.
Am. J. Physiol. Heart Circ. Physiol., 2015 Sep 25 , (ajpheart.00055.2015).

10

Kim KS et al. Rise and Fall of Kir2.2 Current by TLR4 Signaling in Human Monocytes: PKC-Dependent Trafficking and PI3K-Mediated PIP2 Decrease.
J. Immunol., 2015 Oct 1 , 195 (3345-54).

11

Wu Y et al. Two inwardly rectifying potassium channels, Irk1 and Irk2, play redundant roles in Drosophila renal tubule function.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2015 Oct , 309 (R747-56).

12

Yakubovich D et al. A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.
PLoS Comput. Biol., 2015 Nov , 11 (e1004598).

13

Kotecki L et al. GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner.
J. Neurosci., 2015 May 6 , 35 (7131-42).

14

Liu XL et al. Case report: A Chinese child with Andersen-Tawil syndrome due to a de novo KCNJ2 mutation.
J. Neurol. Sci., 2015 May 15 , 352 (105-6).

15

Buck TM et al. The expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiae.
Physiol. Genomics, 2015 Mar 10 , (physiolgenomics.00101.2014).

16

DiFranco M et al. Inward rectifier potassium currents in mammalian skeletal muscle fibres.
J. Physiol. (Lond.), 2015 Mar 1 , 593 (1213-38).

17

Miyamoto K et al. Efficacy and safety of flecainide for ventricular arrhythmias in patients with Andersen-Tawil syndrome with KCNJ2 mutations.
Heart Rhythm, 2015 Mar , 12 (596-603).

18

Hasegawa K et al. Mosaic KCNJ2 mutation in Andersen-Tawil syndrome: targeted deep sequencing is useful for the detection of mosaicism.
Clin. Genet., 2015 Mar , 87 (279-83).

19

Kang S The Role of Casein Kinase 2 in Ion Channel Remodeling After Myocardial Infarction. Editorial to: "Valsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction via Casein Kinase 2" by Xinran Li et al.
Cardiovasc Drugs Ther, 2015 Jun , 29 (207-8).

20

Jugdutt BI Suppression of Ventricular Arrhythmias After Myocardial Infarction by AT1 Receptor Blockade: Role of the AT2 Receptor and Casein Kinase 2/Kir2.1 Pathway. Editorial to: "Valsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction Via Casein K
Cardiovasc Drugs Ther, 2015 Jun , 29 (201-6).

21

Li X et al. Valsartan Upregulates Kir2.1 in Rats Suffering from Myocardial Infarction via Casein Kinase 2.
Cardiovasc Drugs Ther, 2015 Jun , 29 (209-18).

22

Harrell DT et al. Genotype-dependent differences in age of manifestation and arrhythmia complications in short QT syndrome.
Int. J. Cardiol., 2015 Jul 1 , 190 (393-402).

23

Wu ZJ et al. Characterization of a Chinese KCNQ1 mutation (R259H) that shortens repolarization and causes short QT syndrome 2.
J Geriatr Cardiol, 2015 Jul , 12 (394-401).

24

Hsieh CP et al. Driving force-dependent block by internal Ba(2+) on the Kir2.1 channel: Mechanistic insight into inward rectification.
Biophys. Chem., 2015 Jul , 202 (40-57).

25

Cordeiro JM et al. Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization.
J. Mol. Cell. Cardiol., 2015 Jul , 84 (52-60).

26

Chong E et al. Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation.
Heart Rhythm, 2015 Jan 30 , ().

27

Sacco S et al. The inward rectifier potassium channel Kir2.1 is required for osteoblastogenesis.
Hum. Mol. Genet., 2015 Jan 15 , 24 (471-9).

28

Masotti A et al. Keppen-Lubinsky syndrome is caused by mutations in the inwardly rectifying K+ channel encoded by KCNJ6.
Am. J. Hum. Genet., 2015 Feb 5 , 96 (295-300).

29

Qi XY et al. Fibroblast inward-rectifier potassium current upregulation in profibrillatory atrial remodeling.
Circ. Res., 2015 Feb 27 , 116 (836-45).

30

Riz M et al. Inwardly rectifying Kir2.1 currents in human β-cells control electrical activity: Characterisation and mathematical modelling.
Biochem. Biophys. Res. Commun., 2015 Feb 26 , ().

31

Amaral AC et al. Prenatal protein malnutrition decreases KCNJ3 and 2DG activity in rat prefrontal cortex.
Neuroscience, 2015 Feb 12 , 286 (79-86).

32

Masia R et al. The inward rectifier potassium channel Kir2.1 is expressed in mouse neutrophils from bone marrow and liver.
Am. J. Physiol., Cell Physiol., 2015 Feb 1 , 308 (C264-76).

33

Kostera-Pruszczyk A et al. Andersen-Tawil syndrome: report of 3 novel mutations and high risk of symptomatic cardiac involvement.
Muscle Nerve, 2015 Feb , 51 (192-6).

34

Gasparoli L et al. New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.
Mol. Pharmacol., 2015 Feb , 87 (183-96).

35

Obergrussberger A et al. Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module.
J Lab Autom, 2015 Dec 23 , ().

36

Li WP et al. [Function and expression of inwardly rectifying potassium channel Kir2.1].
Sheng Li Ke Xue Jin Zhan, 2015 Aug , 46 (287-9).

37

Huang CW et al. Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K⁺ (Kir2.1) channel.
Pflugers Arch., 2015 Aug , 467 (1733-46).

38

Huang Y et al. [Combined transgenic inhibition of CaMKII and Ik1 on cardiac remodeling].
Sheng Li Xue Bao, 2015 Apr 25 , 67 (201-6).

39

Willis BC et al. Protein Assemblies of Sodium and Inward Rectifier Potassium Channels Control Cardiac Excitability and Arrhythmogenesis.
Am. J. Physiol. Heart Circ. Physiol., 2015 Apr 10 , (ajpheart.00176.2015).

40

Lee JY et al. The role of K⁺ conductances in regulating membrane excitability in human gastric corpus smooth muscle.
Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Apr 1 , 308 (G625-33).

41

Okada M et al. A pore forming peptide from spider Lachesana sp. venom induced neuronal depolarization and pain.
Biochim. Biophys. Acta, 2015 Apr , 1850 (657-66).

42

Cannon SC Channelopathies of skeletal muscle excitability.
Compr Physiol, 2015 Apr , 5 (761-90).

43

Ahmed M et al. Down-regulation of inwardly rectifying Kir2.1 K+ channels by human parvovirus B19 capsid protein VP1.
J. Membr. Biol., 2015 Apr , 248 (223-9).

44

Meijer van Putten RM et al. Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1.
Front Physiol, 2015 , 6 (7).

45

Zhang YY et al. Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells.
PLoS ONE, 2015 , 10 (e0138581).

46

Lyu C et al. G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy.
Mol Pain, 2015 , 11 (44).

47

Subramanian M et al. Idiopathic generalized epilepsy and hypokalemic periodic paralysis in a family of South Indian descent.
Case Rep Neurol Med, 2015 , 2015 (906049).

48

Liu H et al. Upregulation of the inwardly rectifying potassium channel Kir2.1 (KCNJ2) modulates multidrug resistance of small-cell lung cancer under the regulation of miR-7 and the Ras/MAPK pathway.
Mol. Cancer, 2015 , 14 (59).

49

Ortega A et al. Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction.
PLoS ONE, 2015 , 10 (e0145518).

50

Chang HK et al. Mechanism for attenuated outward conductance induced by mutations in the cytoplasmic pore of Kir2.1 channels.
Sci Rep, 2015 , 5 (18404).

51

Kamikawa A et al. Decrease in an Inwardly Rectifying Potassium Conductance in Mouse Mammary Secretory Cells after Forced Weaning.
PLoS ONE, 2015 , 10 (e0141131).

52

Okada M et al. Increase in the titer of lentiviral vectors expressing potassium channels by current blockade during viral vector production.
BMC Neurosci, 2015 , 16 (30).

53

Yang Y et al. Diverse Kir expression contributes to distinct bimodal distribution of resting potentials and vasotone responses of arterioles.
PLoS ONE, 2015 , 10 (e0125266).

54

Wu CL et al. A single pair of neurons modulates egg-laying decisions in Drosophila.
PLoS ONE, 2015 , 10 (e0121335).

55

Montalbano A et al. Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
PLoS ONE, 2015 , 10 (e0140369).

56

Saito Y et al. Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker.
PLoS ONE, 2015 , 10 (e0138193).

57

Allegue C et al. Genetic Analysis of Arrhythmogenic Diseases in the Era of NGS: The Complexity of Clinical Decision-Making in Brugada Syndrome.
PLoS ONE, 2015 , 10 (e0133037).

58

Yang Z et al. Effect of adenosine and adenosine receptor antagonist on Müller cell potassium channel in Rat chronic ocular hypertension models.
Sci Rep, 2015 , 5 (11294).

59

Li J et al. Identification of the Conformational transition pathway in PIP2 Opening Kir Channels.
Sci Rep, 2015 , 5 (11289).

60

Charolidi N et al. Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
PLoS ONE, 2015 , 10 (e0128463).

61

Li X et al. The clinical and genetic features in a cohort of mainland Chinese patients with thyrotoxic periodic paralysis.
BMC Neurol, 2015 , 15 (38).

62

Wang Y et al. The Beneficial Effects of Electro-acupuncture at PC6 (Neiguan-point) of Gene and Protein Expressions of Classical Inward-rectifier Potassium Channels in Myocardial Ischemic Rats.
Acupunct Electrother Res, 2015 , 40 (335-53).

63

Márquez MF et al. [Andersen-Tawil syndrome: a review of its clinical and genetic diagnosis with emphasis on cardiac manifestations].
Arch Cardiol Mex, 2014 Oct-Dec , 84 (278-85).

64

Kanbara T et al. Morphine and oxycodone, but not fentanyl, exhibit antinociceptive effects mediated by G-protein inwardly rectifying potassium (GIRK) channels in an oxaliplatin-induced neuropathy rat model.
Neurosci. Lett., 2014 Sep 19 , 580 (119-24).

65

Kupferman JV et al. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment.
Cell, 2014 Sep 11 , 158 (1335-47).

66

Rosenhouse-Dantsker A et al. Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2.
Comput Struct Biotechnol J, 2014 Sep , 11 (131-7).

67

Houtman MJ et al. Insights in KIR2.1 channel structure and function by an evolutionary approach; cloning and functional characterization of the first reptilian inward rectifier channel KIR2.1, derived from the California kingsnake (Lampropeltis getula californiae).
Biochem. Biophys. Res. Commun., 2014 Oct 3 , 452 (992-7).

68

Singhal R et al. Colchicine suppresses atrial fibrillation in failing heart.
Int. J. Cardiol., 2014 Oct 20 , 176 (651-60).

69

Shi D et al. Reduction in dynamin-2 is implicated in ischaemic cardiac arrhythmias.
J. Cell. Mol. Med., 2014 Oct , 18 (1992-9).

70

Wen W et al. Discovery of potent and selective GIRK1/2 modulators via 'molecular switches' within a series of 1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ureas.
Bioorg. Med. Chem. Lett., 2014 Nov 1 , 24 (5102-6).

71

Gómez R et al. Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.
Cardiovasc. Res., 2014 Nov 1 , 104 (337-46).

72

Shen N et al. Barium chloride impaired Kir2.1 inward rectification in its stably transfected HEK 293 cell lines.
Eur. J. Pharmacol., 2014 May 5 , 730 (164-70).

73

Longden TA et al. Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function.
Proc. Natl. Acad. Sci. U.S.A., 2014 May 20 , 111 (7462-7).

74

Wang X et al. The predisposition to thyrotoxic periodic paralysis (TPP) is due to a genetic variant in the inward-rectifying potassium channel, KCNJ2.
Clin. Endocrinol. (Oxf), 2014 May , 80 (770-1).

75

Zhang YY et al. Characterization of functional ion channels in human cardiac c-kit+ progenitor cells.
Basic Res. Cardiol., 2014 May , 109 (407).

76

Kalscheur MM et al. KCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia.
Heart Rhythm, 2014 May , 11 (885-94).

77

Hartman ME et al. Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.
FASEB J., 2014 Mar 31 , ().

78

Kokunai Y et al. A Kir3.4 mutation causes Andersen-Tawil syndrome by an inhibitory effect on Kir2.1.
Neurology, 2014 Mar 25 , 82 (1058-64).

79

Huang CW et al. Gating of the Kir2.1 Channel at the Bundle Crossing Region by Intracellular Spermine and Other Cations.
J. Cell. Physiol., 2014 Mar 14 , ().

80

Raphemot R et al. Direct activation of β-cell KATP channels with a novel xanthine derivative.
Mol. Pharmacol., 2014 Jun , 85 (858-65).

81

Wydeven N et al. Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.
Proc. Natl. Acad. Sci. U.S.A., 2014 Jul 22 , 111 (10755-60).

82

Hassinen M et al. Seasonal acclimatization of the cardiac action potential in the Arctic navaga cod (Eleginus navaga, Gadidae).
J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol., 2014 Jan 7 , ().

83

Qu YH et al. Remodeling of ion channel expression may contribute to electrophysiological consequences caused by methamphetamine in vitro and in vivo.
Biochem. Biophys. Res. Commun., 2014 Jan 10 , 443 (441-6).

84

Liang B et al. G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization.
Cardiovasc. Res., 2014 Jan 1 , 101 (175-84).

85

Kolb AR et al. ESCRT regulates surface expression of the Kir2.1 potassium channel.
Mol. Biol. Cell, 2014 Jan , 25 (276-89).

86

Mints Y et al. Single nucleotide polymorphisms in proximity to K-channel genes are associated with decreased longitudinal QTc variance.
Ann Noninvasive Electrocardiol, 2014 Jan , 19 (63-9).

87

Geraldes V et al. Chronic depression of hypothalamic paraventricular neuronal activity produces sustained hypotension in hypertensive rats.
Exp. Physiol., 2014 Jan , 99 (89-100).

88

Chung MK et al. Peripheral G protein-coupled inwardly rectifying potassium channels are involved in δ-opioid receptor-mediated anti-hyperalgesia in rat masseter muscle.
Eur J Pain, 2014 Jan , 18 (29-38).

89

Sheng J et al. Electrophysiology of human cardiac atrial and ventricular telocytes.
J. Cell. Mol. Med., 2014 Feb , 18 (355-62).

90

Marquis-Nicholson R et al. Array comparative genomic hybridization identifies a heterozygous deletion of the entire KCNJ2 gene as a cause of sudden cardiac death.
Circ Cardiovasc Genet, 2014 Feb , 7 (17-22).

91

Huang CW et al. The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channel.
Pflugers Arch., 2014 Feb , 466 (275-93).

92

Fürst O et al. Identification of a cholesterol-binding pocket in inward rectifier K(+) (Kir) channels.
Biophys. J., 2014 Dec 16 , 107 (2786-96).

93

Kahanovitch U et al. Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.
J. Physiol. (Lond.), 2014 Dec 15 , 592 (5373-90).

94

Geraldes V et al. Essential role of RVL medullary neuronal activity in the long term maintenance of hypertension in conscious SHR.
Auton Neurosci, 2014 Dec , 186 (22-31).

95

Xynogalos P et al. Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224.
Naunyn Schmiedebergs Arch. Pharmacol., 2014 Dec , 387 (1153-61).

96

Lefter S et al. Andersen-Tawil syndrome with early fixed myopathy.
J Clin Neuromuscul Dis, 2014 Dec , 16 (79-82).

97

Kukla P et al. Electrocardiogram in Andersen-Tawil syndrome. New electrocardiographic criteria for diagnosis of type-1 Andersen-Tawil syndrome.
Curr Cardiol Rev, 2014 Aug , 10 (222-8).

98

Rinné S et al. A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels.
Pflugers Arch., 2014 Aug , 466 (1559-70).

99

Díaz-Manera J et al. Severe exacerbation of Andersen-Tawil syndrome secondary to thyrotoxicosis.
J. Hum. Genet., 2014 Aug , 59 (465-6).

100

Weeke P et al. Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome.
J. Am. Coll. Cardiol., 2014 Apr 15 , 63 (1430-7).

101

Farhy Tselnicker I et al. Dual regulation of G proteins and the G-protein-activated K+ channels by lithium.
Proc. Natl. Acad. Sci. U.S.A., 2014 Apr 1 , 111 (5018-23).

102

Sivagangabalan G et al. Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.
PLoS ONE, 2014 , 9 (e82179).

103

Iyer V et al. Modeling Tissue- and Mutation- Specific Electrophysiological Effects in the Long QT Syndrome: Role of the Purkinje Fiber.
PLoS ONE, 2014 , 9 (e97720).

104

Munoz C et al. Up-regulation of Kir2.1 (KCNJ2) by the serum & glucocorticoid inducible SGK3.
Cell. Physiol. Biochem., 2014 , 33 (491-500).

105

Burridge PW et al. Multi-cellular interactions sustain long-term contractility of human pluripotent stem cell-derived cardiomyocytes.
Am J Transl Res, 2014 , 6 (724-35).

106

Zapata M et al. Molecular cloning of ion channels in Felis catus that are related to periodic paralyses in man: a contribution to the understanding of the genetic susceptibility to feline neck ventroflexion and paralysis.
Biol Open, 2014 , 3 (785-93).

107

Kito H et al. Membrane hyperpolarization induced by endoplasmic reticulum stress facilitates ca(2+) influx to regulate cell cycle progression in brain capillary endothelial cells.
J. Pharmacol. Sci., 2014 , 125 (227-32).

108

Yu CC et al. Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currents.
PLoS ONE, 2014 , 9 (e96691).

109

Kumar M et al. Focus on Kir7.1: physiology and channelopathy.
Channels (Austin), 2014 , 8 (488-95).

110

Liang S et al. Carbon monoxide inhibits inward rectifier potassium channels in cardiomyocytes.
Nat Commun, 2014 , 5 (4676).

111

Rosenhouse-Dantsker A et al. Identification of novel cholesterol-binding regions in Kir2 channels.
J. Biol. Chem., 2013 Sep 9 , ().

112

Duan X Ion Channels, Channelopathies, and Tooth Formation.
J. Dent. Res., 2013 Sep 27 , ().

113

Ramos-Hunter SJ et al. Discovery and SAR of a novel series of GIRK1/2 and GIRK1/4 activators.
Bioorg. Med. Chem. Lett., 2013 Sep 15 , 23 (5195-8).

114

Cordeiro JM et al. Developmental changes in expression and biophysics of ion channels in the canine ventricle.
J. Mol. Cell. Cardiol., 2013 Sep 10 , 64C (79-89).

115

Fernlund E et al. Novel mutation in the KCNJ2 gene is associated with a malignant arrhythmic phenotype of Andersen-Tawil syndrome.
Ann Noninvasive Electrocardiol, 2013 Sep , 18 (471-8).

116

Zhang L et al. Zacopride selectively activates the Kir2.1 channel via a PKA signaling pathway in rat cardiomyocytes.
Sci China Life Sci, 2013 Sep , 56 (788-96).

117

Olesen MS et al. Very early onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation.
Heart Rhythm, 2013 Oct 18 , ().

118

Kang JY et al. In vivo expression of a light-activatable potassium channel using unnatural amino acids.
Neuron, 2013 Oct 16 , 80 (358-70).

119

Hasegawa K et al. A Novel KCNQ1 Missense Mutation Identified in a Patient with Juvenile-Onset Atrial Fibrillation Causes Constitutively Open IKs Channels.
Heart Rhythm, 2013 Oct 1 , ().

120

Gunnarsson TP et al. Effect of intensified training on muscle ion kinetics, fatigue development, and repeated short-term performance in endurance-trained cyclists.
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2013 Oct , 305 (R811-R821).

121

Lee YS et al. Long QT syndrome: a Korean single center study.
J. Korean Med. Sci., 2013 Oct , 28 (1454-60).

122

Eleawa SM et al. Effect of testosterone replacement therapy on cardiac performance and oxidative stress in orchidectomized rats.
Acta Physiol (Oxf), 2013 Oct , 209 (136-47).

123

Jabbari J et al. New exome data question the pathogenicity of genetic variants previously associated with catecholaminergic polymorphic ventricular tachycardia.
Circ Cardiovasc Genet, 2013 Oct , 6 (481-9).

124

Muessel MJ et al. SDF-1α and LPA modulate microglia potassium channels through rho gtpases to regulate cell morphology.
Glia, 2013 Oct , 61 (1620-8).

125

Wu XN et al. Sucrose-induced receptor kinase SIRK1 regulates a plasma membrane aquaporin in Arabidopsis.
Mol. Cell Proteomics, 2013 Oct , 12 (2856-73).

126

Mishra B et al. Sodium and potassium currents influence Wallerian degeneration of injured Drosophila axons.
J. Neurosci., 2013 Nov 27 , 33 (18728-39).

127

Kamikawa A et al. Functional expression of a Kir2.1-like inwardly rectifying potassium channel in mouse mammary secretory cells.
Am. J. Physiol., Cell Physiol., 2013 Nov 20 , ().

128

Waters CW et al. Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction.
Proc. Natl. Acad. Sci. U.S.A., 2013 May 28 , 110 (9160-5).

129

Luo X et al. MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation.
J. Clin. Invest., 2013 May 1 , 123 (1939-51).

130

Deo M et al. KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia.
Proc. Natl. Acad. Sci. U.S.A., 2013 Mar 12 , 110 (4291-6).

131

Munoz C et al. Up-regulation of the inwardly rectifying K⁺ channel Kir2.1 (KCNJ2) by protein kinase B (PKB/Akt) and PIKfyve.
J. Membr. Biol., 2013 Mar , 246 (189-97).

132

Saenz del Burgo L et al. Chronic effects of corticosterone on GIRK1-3 subunits and 5-HT1A receptor expression in rat brain and their reversal by concurrent fluoxetine treatment.
Eur Neuropsychopharmacol, 2013 Mar , 23 (229-39).

133

D'Avanzo N et al. Energetics and location of phosphoinositide binding in human Kir2.1 channels.
J. Biol. Chem., 2013 Jun 7 , 288 (16726-37).

134

Rosenhouse-Dantsker A et al. Cholesterol sensitivity of KIR2.1 depends on Functional inter-links between the N and C termini.
Channels (Austin), 2013 Jun 27 , 7 ().

135

Vaidyanathan R et al. The Interaction of Caveolin 3 Protein with the Potassium Inward Rectifier Channel Kir2.1: PHYSIOLOGY AND PATHOLOGY RELATED TO LONG QT SYNDROME 9 (LQT9).
J. Biol. Chem., 2013 Jun 14 , 288 (17472-80).

136

Bates EA A potential molecular target for morphological defects of fetal alcohol syndrome: Kir2.1.
Curr. Opin. Genet. Dev., 2013 Jun , 23 (324-9).

137

Jost N et al. Ionic mechanisms limiting cardiac repolarization-reserve in humans compared to dogs.
J. Physiol. (Lond.), 2013 Jul 22 , ().

138

Kiss T et al. Identification of diterpene alkaloids from Aconitum napellus subsp. firmum and GIRK channel activities of some Aconitum alkaloids.
Fitoterapia, 2013 Jul 19 , ().

139

Amorós I et al. Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore.
Biochem. Pharmacol., 2013 Jul 15 , 86 (267-78).

140

Okada M et al. The degradation of the inwardly rectifying potassium channel, Kir2.1, depends on the expression level: Examination with fluorescent proteins.
Brain Res., 2013 Jul 11 , ().

141

Takanari H et al. Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue.
Cardiovasc. Res., 2013 Jul 1 , 99 (203-14).

142

Lai PF et al. Mesenchymal stem cell transplantation mitigates electrophysiological remodeling in a rat model of myocardial infarction.
J. Cardiovasc. Electrophysiol., 2013 Jul , 24 (813-21).

143

Nam TS et al. An algorithm for candidate sequencing in non-dystrophic skeletal muscle channelopathies.
J. Neurol., 2013 Jul , 260 (1770-7).

144

Lieve KV et al. Results of genetic testing in 855 consecutive unrelated patients referred for long QT syndrome in a clinical laboratory.
Genet Test Mol Biomarkers, 2013 Jul , 17 (553-61).

145

Ford J et al. Human Electrophysiological and Pharmacological Properties of XEN-D0101: A Novel Atrial Selective Kv1.5/IKur Inhibitor.
J. Cardiovasc. Pharmacol., 2013 Jan 29 , ().

146

Liu L et al. A novel mutation in the transmembrane nonpore region of the KCNH2 gene causes severe clinical manifestations of long QT syndrome.
Heart Rhythm, 2013 Jan , 10 (61-7).

147

Hilder TA et al. Conduction and block of inward rectifier K+ channels: predicted structure of a potent blocker of Kir2.1.
Biochemistry, 2013 Feb 5 , 52 (967-74).

148

Yamamoto Y et al. Amiodarone inhibits tissue factor expression in monocytic THP-1 cells.
Eur. J. Pharmacol., 2013 Feb 15 , 701 (14-9).

149

Lieu DK et al. Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes.
Circ Arrhythm Electrophysiol, 2013 Feb , 6 (191-201).

150

Chang HK et al. Voltage-dependent inhibition of outward Kir2.1 currents by extracellular spermine.
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