Channelpedia

Kv7.3

283 literature references associated to Kv7.3

used / unused
Pubmed id

1

361613

Schütze S et al. KCNQ Potassium Channels Modulate Sensitivity of Skin D-hair Mechanoreceptors.
J. Biol. Chem., 2016 Jan 5 , ().

9

357547

10

367927

Kaminsky Z et al. DNA methylation and expression of KCNQ3 in bipolar disorder.
Bipolar Disord, 2015 Mar , 17 (150-9).

13

357396

14

367846

15

358595

20

363550

21

366356

Zhang F et al. Inhibition of Kv7/M Channel Currents by the Local Anesthetic Chloroprocaine.
Pharmacology, 2015 , 96 (124-30).

22

350877

Allen NM et al. The variable phenotypes of KCNQ-related epilepsy.
Epilepsia, 2014 Sep , 55 (e99-105).

23

361007

Grigorov A et al. Kv7 potassium channel subunits and M currents in cultured hippocampal interneurons.
Pflugers Arch., 2014 Sep , 466 (1747-58).

24

355586

King CH et al. Kv7.2 regulates the function of peripheral sensory neurons.
J. Comp. Neurol., 2014 Oct 1 , 522 (3262-80).

28

352449

29

345951

Brueggemann LI et al. KCNQ (Kv7) potassium channel activators as bronchodilators: combination with a β2-adrenergic agonist enhances relaxation of rat airways.
Am. J. Physiol. Lung Cell Mol. Physiol., 2014 Mar 15 , 306 (L476-86).

30

346212

33

349610

Gourgy-Hacohen O et al. Capturing distinct KCNQ2 channel resting states by metal ion bridges in the voltage-sensor domain.
J. Gen. Physiol., 2014 Dec , 144 (513-27).

35

352810

36

355867

Maljevic S et al. Potassium channel genes and benign familial neonatal epilepsy.
Prog. Brain Res., 2014 , 213 (17-53).

38

347792

Svalø J et al. Bladder contractility is modulated by Kv7 channels in pig detrusor.
Eur. J. Pharmacol., 2013 Sep 5 , 715 (312-20).

40

340210

41

343901

Fister P et al. Benign familial neonatal convulsions caused by mutation in KCNQ3, exon 6: a European case.
Eur. J. Paediatr. Neurol., 2013 May , 17 (308-10).

44

341023

48

343871

Lichter-Peled A et al. Role of KCNQ2 and KCNQ3 genes in juvenile idiopathic epilepsy in Arabian foals.
Vet. J., 2013 Apr , 196 (57-63).

51

346962

Robbins J et al. Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
PLoS ONE, 2013 , 8 (e71809).

53

354543

Ferrer T et al. Tamoxifen inhibition of kv7.2/kv7.3 channels.
PLoS ONE, 2013 , 8 (e76085).

54

339112

56

327410

57

329817

58

327036

Pattnaik BR et al. Effects of KCNQ channel modulators on the M-type potassium current in primate retinal pigment epithelium.
Am. J. Physiol., Cell Physiol., 2012 Mar , 302 (C821-33).

59

332284

Choveau FS et al. Pore helix-S6 interactions are critical in governing current amplitudes of KCNQ3 K+ channels.
Biophys. J., 2012 Jun 6 , 102 (2499-509).

60

332285

Choveau FS et al. Pore determinants of KCNQ3 K+ current expression.
Biophys. J., 2012 Jun 6 , 102 (2489-98).

62

330117

King CH et al. Kv7.5 is the primary Kv7 subunit expressed in C-fibers.
J. Comp. Neurol., 2012 Jun 15 , 520 (1940-50).

63

332394

Telezhkin V et al. Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2.
J. Gen. Physiol., 2012 Jul , 140 (41-53).

64

325660

Weckhuysen S et al. KCNQ2 encephalopathy: emerging phenotype of a neonatal epileptic encephalopathy.
Ann. Neurol., 2012 Jan , 71 (15-25).

65

328995

Linley JE et al. M channel enhancers and physiological M channel block.
J. Physiol. (Lond.), 2012 Feb 15 , 590 (793-807).

66

327817

Chege SW et al. Expression and function of KCNQ channels in larval zebrafish.
Dev Neurobiol, 2012 Feb , 72 (186-98).

67

328687

Stewart AP et al. The Kv7.2/Kv7.3 heterotetramer assembles with a random subunit arrangement.
J. Biol. Chem., 2012 Apr 6 , 287 (11870-7).

73

324074

Klinger F et al. Distribution of M-channel subunits KCNQ2 and KCNQ3 in rat hippocampus.
Neuroimage, 2011 Oct 1 , 58 (761-9).

75

317263

Zhang J et al. AKAP79/150 Signal Complexes in G-Protein Modulation of Neuronal Ion Channels.
J. Neurosci., 2011 May 11 , 31 (7199-211).

76

316523

McCallum LA et al. The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.
J. Cell. Mol. Med., 2011 Mar , 15 (577-86).

79

320904

Roepke TA et al. Fasting and 17β-estradiol differentially modulate the M-current in neuropeptide Y neurons.
J. Neurosci., 2011 Aug 17 , 31 (11825-35).

82

139401

Zhong XZ et al. Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter.
J. Physiol. (Lond.), 2010 Sep 1 , 588 (3277-93).

84

140532

85

140237

Lötsch J et al. Pharmacogenetics of new analgesics.
, 2010 Oct 13 , ().

86

138433

Tzingounis AV et al. The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.
Proc. Natl. Acad. Sci. U.S.A., 2010 Jun 1 , 107 (10232-7).

87

139061

Gómez-Posada JC et al. A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression.
J. Neurosci., 2010 Jul 7 , 30 (9316-23).

88

136876

89

315375

Serratrice G et al. [Potassium channelopathies and Morvan's syndromes].
Bull. Acad. Natl. Med., 2010 Feb , 194 (391-406; discussion 406-7).

90

139529

Baulac S et al. Advances on the genetics of mendelian idiopathic epilepsies.
Clin. Lab. Med., 2010 Dec , 30 (911-29).

93

121425

95

123705

96

122559

Padilla K et al. The KCNQ2/3 selective channel opener ICA-27243 binds to a novel voltage-sensor domain site.
Neurosci. Lett., 2009 Nov 13 , 465 (138-42).

97

122836

Goldberg-Stern H et al. Novel mutation in KCNQ2 causing benign familial neonatal seizures.
Pediatr. Neurol., 2009 Nov , 41 (367-70).

98

123079

Baulac S et al. Advances on the genetics of mendelian idiopathic epilepsies.
Neurol Clin, 2009 Nov , 27 (1041-61).

99

123507

101

678

104

5583

Greenwood IA et al. KCNQ-encoded channels regulate Na+ transport across H441 lung epithelial cells.
Pflugers Arch., 2009 Feb , 457 (785-94).

106

121979

de Mooij-van Malsen AJ et al. Interspecies trait genetics reveals association of Adcy8 with mouse avoidance behavior and a human mood disorder.
Biol. Psychiatry, 2009 Dec 15 , 66 (1123-30).

107

123486

108

122637

Brown DA et al. Neural KCNQ (Kv7) channels.
Br. J. Pharmacol., 2009 Apr , 156 (1185-95).

109

6257

110

8071

Wickenden AD et al. Kv7 channels as targets for the treatment of pain.
Curr. Pharm. Des., 2009 , 15 (1773-98).

111

122891

Roura-Ferrer M et al. Functional implications of KCNE subunit expression for the Kv7.5 (KCNQ5) channel.
Cell. Physiol. Biochem., 2009 , 24 (325-34).

116

5055

117

9812

Bal M et al. Calmodulin binding to M-type K+ channels assayed by TIRF/FRET in living cells.
J. Physiol. (Lond.), 2008 May 1 , 586 (2307-20).

123

9534

Shah MM et al. Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons.
Proc. Natl. Acad. Sci. U.S.A., 2008 Jun 3 , 105 (7869-74).

126

9550

Neubauer BA et al. KCNQ2 and KCNQ3 mutations contribute to different idiopathic epilepsy syndromes.
Neurology, 2008 Jul 15 , 71 (177-83).

127

7866

Schuetz F et al. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1.
Am. J. Physiol., Cell Physiol., 2008 Jul , 295 (C73-80).

128

6185

Fedorenko O et al. A schizophrenia-linked mutation in PIP5K2A fails to activate neuronal M channels.
Psychopharmacology (Berl.), 2008 Jul , 199 (47-54).

130

6247

Xiong Q et al. Combinatorial augmentation of voltage-gated KCNQ potassium channels by chemical openers.
Proc. Natl. Acad. Sci. U.S.A., 2008 Feb 26 , 105 (3128-33).

131

14699

Wladyka CL et al. The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats.
J. Physiol. (Lond.), 2008 Feb 1 , 586 (795-802).

134

660

Tzingounis AV et al. Contribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currents.
Proc. Natl. Acad. Sci. U.S.A., 2008 Dec 16 , 105 (19974-9).

136

1937

Hansen HH et al. Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1823-32).

137

2188

Hernandez CC et al. Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1811-21).

138

8514

Maljevic S et al. Nervous system KV7 disorders: breakdown of a subthreshold brake.
J. Physiol. (Lond.), 2008 Apr 1 , 586 (1791-801).

142

13348

Lucarini N et al. Genetic polymorphisms and idiopathic generalized epilepsies.
Pediatr. Neurol., 2007 Sep , 37 (157-64).

143

18041

Roepke TA et al. Estrogen regulation of genes important for K+ channel signaling in the arcuate nucleus.
Endocrinology, 2007 Oct , 148 (4937-51).

144

10979

145

10048

Bai X et al. Electrophysiological properties of human adipose tissue-derived stem cells.
Am. J. Physiol., Cell Physiol., 2007 Nov , 293 (C1539-50).

148

17749

150

16683

Heron SE et al. Deletions or duplications in KCNQ2 can cause benign familial neonatal seizures.
J. Med. Genet., 2007 Dec , 44 (791-6).

152

14311

153

16657

Jensen HS et al. Inactivation as a new regulatory mechanism for neuronal Kv7 channels.
Biophys. J., 2007 Apr 15 , 92 (2747-56).

155

13966

156

10755

Lawrence JJ et al. Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons.
J. Neurosci., 2006 Nov 22 , 26 (12325-38).

157

15078

Bentzen BH et al. The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.
Neuropharmacology, 2006 Nov , 51 (1068-77).

158

28888

Geiger J et al. Immunohistochemical analysis of KCNQ3 potassium channels in mouse brain.
Neurosci. Lett., 2006 May 29 , 400 (101-4).

159

25580

Schwarz JR et al. KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier.
J. Physiol. (Lond.), 2006 May 15 , 573 (17-34).

162

22427

165

139001

168

20693

Suh BC et al. Does diacylglycerol regulate KCNQ channels?
Pflugers Arch., 2006 Dec , 453 (293-301).

169

17989

Gardiner M Molecular genetics of infantile nervous system channelopathies.
Early Hum. Dev., 2006 Dec , 82 (775-9).

170

19405

Li HY et al. [Clinical and mutational analysis of KCNQ3 gene in a Chinese family with benign familial neonatal convulsions]
Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2006 Aug , 23 (374-7).

171

20398

Schwake M et al. Structural determinants of M-type KCNQ (Kv7) K+ channel assembly.
J. Neurosci., 2006 Apr 5 , 26 (3757-66).

172

20131

173

28846

Shahidullah M et al. Expression of a calmodulin-binding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability.
Proc. Natl. Acad. Sci. U.S.A., 2005 Nov 8 , 102 (16454-9).

174

28886

Schenzer A et al. Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.
J. Neurosci., 2005 May 18 , 25 (5051-60).

176

24641

Wang X et al. [Advances in the studies on the molecular and genetic aspects of epilepsy]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 2005 Jun , 27 (388-93).

177

23241

Wolff C et al. [3H]linopirdine binding to rat brain membranes is not relevant for M-channel interaction.
Eur. J. Pharmacol., 2005 Jul 25 , 518 (10-7).

178

27576

Surti TS et al. A potassium channel, the M-channel, as a therapeutic target.
, 2005 Jul , 6 (704-11).

180

23280

185

25163

Wua YJ et al. Recent developments on KCNQ potassium channel openers.
Curr. Med. Chem., 2005 , 12 (453-60).

186

24049

Liang G et al. An M-like potassium current in the guinea pig cochlea.
ORL J. Otorhinolaryngol. Relat. Spec., 2005 , 67 (75-82).

187

22929

Gardiner M Genetics of idiopathic generalized epilepsies.
Epilepsia, 2005 , 46 Suppl 9 (15-20).

188

27647

Burgess DL Neonatal epilepsy syndromes and GEFS+: mechanistic considerations.
Epilepsia, 2005 , 46 Suppl 10 (51-8).

190

37119

191

39207

Etxeberria A et al. Three mechanisms underlie KCNQ2/3 heteromeric potassium M-channel potentiation.
J. Neurosci., 2004 Oct 13 , 24 (9146-52).

192

39753

Kelemen A et al. [Genetic background of epilepsies]
, 2004 May 20 , 57 (141-51).

193

38339

195

30149

197

30467

199

38183

Devaux JJ et al. KCNQ2 is a nodal K+ channel.
J. Neurosci., 2004 Feb 4 , 24 (1236-44).

200

32503

Avramopoulos D et al. Linkage of bipolar affective disorder on chromosome 8q24: follow-up and parametric analysis.
Mol. Psychiatry, 2004 Feb , 9 (191-6).

201

35021

Claes LR et al. De novo KCNQ2 mutations in patients with benign neonatal seizures.
Neurology, 2004 Dec 14 , 63 (2155-8).

205

42389

Grunnet M et al. KCNQ1 channels sense small changes in cell volume.
J. Physiol. (Lond.), 2003 Jun 1 , 549 (419-27).

206

41225

207

43171

Zhang ZH et al. Inhibitory effects of pimozide on cloned and native voltage-gated potassium channels.
Brain Res. Mol. Brain Res., 2003 Jul 4 , 115 (29-38).

208

41367

Gamper N et al. Subunit-specific modulation of KCNQ potassium channels by Src tyrosine kinase.
J. Neurosci., 2003 Jan 1 , 23 (84-95).

209

45265

211

45763

Okada M et al. Age-dependent modulation of hippocampal excitability by KCNQ-channels.
Epilepsy Res., 2003 Feb , 53 (81-94).

213

30670

214

33914

Gribkoff VK The therapeutic potential of neuronal KCNQ channel modulators.
Expert Opin. Ther. Targets, 2003 Dec , 7 (737-48).

215

36066

Li HY et al. [A novel mutation of KCNQ2 gene in a Chinese family with benign familial neonatal convulsions]
Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2003 Dec , 20 (482-5).

216

48592

Maljevic S et al. C-terminal interaction of KCNQ2 and KCNQ3 K+ channels.
J. Physiol. (Lond.), 2003 Apr 15 , 548 (353-60).

217

45642

Cooper EC et al. M-channels: neurological diseases, neuromodulation, and drug development.
Arch. Neurol., 2003 Apr , 60 (496-500).

218

48040

219

42624

Wen H et al. Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels.
J. Neurosci., 2002 Sep 15 , 22 (7991-8001).

220

40993

221

44171

Shah MM et al. Molecular correlates of the M-current in cultured rat hippocampal neurons.
J. Physiol. (Lond.), 2002 Oct 1 , 544 (29-37).

223

54821

224

48784

227

43621

Guo J et al. Histamine inhibits KCNQ2/KCNQ3 channel current via recombinant histamine H(1) receptors.
Neurosci. Lett., 2002 Aug 16 , 328 (285-8).

230

41250

Steinlein OK Channelopathies can cause epilepsy in man.
, 2002 , 6 Suppl A (27-34).

231

43494

Okada M et al. Impaired M-current and neuronal excitability.
Epilepsia, 2002 , 43 Suppl 9 (36-8).

232

54231

Steinlein OK Genes and mutations in idiopathic epilepsy.
Am. J. Med. Genet., 2001 Summer , 106 (139-45).

233

58439

Lerche H et al. Ion channels and epilepsy.
Am. J. Med. Genet., 2001 Summer , 106 (146-59).

234

54297

Dedek K et al. Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel.
Proc. Natl. Acad. Sci. U.S.A., 2001 Oct 9 , 98 (12272-7).

236

50593

Moulard B et al. Ion channel variation causes epilepsies.
Brain Res. Brain Res. Rev., 2001 Oct , 36 (275-84).

237

54466

Korolkova YV et al. An ERG channel inhibitor from the scorpion Buthus eupeus.
J. Biol. Chem., 2001 Mar 30 , 276 (9868-76).

239

58896

Schrøder RL et al. KCNQ4 channel activation by BMS-204352 and retigabine.
Neuropharmacology, 2001 Jun , 40 (888-98).

240

59247

241

57040

Selyanko AA et al. Properties of single M-type KCNQ2/KCNQ3 potassium channels expressed in mammalian cells.
J. Physiol. (Lond.), 2001 Jul 1 , 534 (15-24).

242

52404

Wickenden AD et al. Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells.
Br. J. Pharmacol., 2001 Jan , 132 (381-4).

246

56715

Robbins J KCNQ potassium channels: physiology, pathophysiology, and pharmacology.
Pharmacol. Ther., 2001 Apr , 90 (1-19).

248

54388

Tinel N et al. M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit.
FEBS Lett., 2000 Sep 1 , 480 (137-41).

249

59248

251

62025

252

51979

Gardiner RM Impact of our understanding of the genetic aetiology of epilepsy.
J. Neurol., 2000 May , 247 (327-34).

254

62615

255

56645

Kananura C et al. The new voltage gated potassium channel KCNQ5 and neonatal convulsions.
Neuroreport, 2000 Jun 26 , 11 (2063-7).

259

55341

Watanabe H et al. Disruption of the epilepsy KCNQ2 gene results in neural hyperexcitability.
J. Neurochem., 2000 Jul , 75 (28-33).

260

60079

262

64803

Hadley JK et al. Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels.
Br. J. Pharmacol., 2000 Feb , 129 (413-5).

263

66501

264

51782

Schroeder BC et al. KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currents.
J. Biol. Chem., 2000 Aug 4 , 275 (24089-95).

265

54488

Main MJ et al. Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine.
Mol. Pharmacol., 2000 Aug , 58 (253-62).

266

55655

267

60643

Cooper EC et al. Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy.
Proc. Natl. Acad. Sci. U.S.A., 2000 Apr 25 , 97 (4914-9).

269

60944

Lerche H et al. A reduced K+ current due to a novel mutation in KCNQ2 causes neonatal convulsions.
Ann. Neurol., 1999 Sep , 46 (305-12).

270

62311

271

63713

Rho JM et al. Developmental seizure susceptibility of kv1.1 potassium channel knockout mice.
Dev. Neurosci., 1999 Nov , 21 (320-7).

272

65987

McCormack T et al. Chromosomal mapping of the potassium channel genes Kcnq2 and Kcnq3 in mouse.
Genomics, 1999 Mar 15 , 56 (360-1).

273

65681

Meves H et al. Separation of M-like current and ERG current in NG108-15 cells.
Br. J. Pharmacol., 1999 Jul , 127 (1213-23).

274

60150

Hirsch E et al. [Benign familial neonatal convulsions: a model of idiopathic epilepsy]
Rev. Neurol. (Paris), 1999 Jul , 155 (463-7).

275

65825

Steinlein OK et al. The voltage gated potassium channel KCNQ2 and idiopathic generalized epilepsy.
Neuroreport, 1999 Apr 26 , 10 (1163-6).

276

66107

Steinlein OK Idiopathic epilepsies with a monogenic mode of inheritance.
Epilepsia, 1999 , 40 Suppl 3 (9-11).

277

68853

Leppert MF et al. Susceptibility genes in human epilepsy.
, 1999 , 19 (397-405).

280

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281

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282

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283

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