Channelpedia

PubMed 15290763


Referenced in: none

Automatically associated channels: HCN1 , HCN3 , HCN4



Title: An interactive tool for extracting exons and SNP from genomic sequence: isolation of HCN1 and HCN3 ion channel genes.

Authors: Yuan Liu, Yuhong Wang, Kimberly Folander, Guochun Xie, Richard Blevins

Journal, date & volume: , 2003 Oct , 1, 433-46

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/15290763


Abstract
Genome Analyzer (GenoA) with a relational database back-end, was developed to extract information from mammalian genomic sequences. This data mining and visualization tool-set enables laboratory bench scientists to identify and assemble virtual cDNA from genomic exon sequences, and provides a starting point to identify potential alternative splice variants and polymorphisms in silico. The study described in this paper demonstrates the use of GenoA to study human brain hyperpolarization-activated cation channel genes HCN1 and HCN3.