Channelpedia

PubMed 24926793


Referenced in: none

Automatically associated channels: Cav1.2



Title: AKAP5 keeps L-type channels and NFAT on their toes.

Authors: Manuel F Navedo, Johannes W Hell

Journal, date & volume: Cell Rep, 2014 Jun 12 , 7, 1341-2

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/24926793


Abstract
In this issue of Cell Reports, Murphy et al. and Dittmer et al. present exciting new insight into the regulation of Ca2+ influx via the L-type Ca2+ channel Cav1.2 and how increased Ca2+ influx translates into localized activation of the nuclear transcription factor NFAT upon depolarization in neurons.