Referenced in: none

Automatically associated channels: Kir1.1 , Kir6.2

Title: Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea.

Authors: Chiara Russo, Alessandro Salina, Concetta Aloi, Dario Iafusco, Renata Lorini, Giuseppe d'Annunzio

Journal, date & volume: Diabetes Res. Clin. Pract., 2011 Nov , 94, e50-2

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/21871684

Abstract
KCNJ11 gene mutations are related to permanent neonatal diabetes mellitus (PNDM). Glycemic stability minimizes the risk of complications. Sulfonylureas (SU) are the proven best therapeutic option. We report a 18-month follow-up of switching from insulin to SU in a mother and her daughter with PNDM due to KCNJ11 mutation.