PubMed 10449331

Title: Inwardly rectifying potassium channels.

Authors: F Reimann, F M Ashcroft

Journal, date & volume: Curr. Opin. Cell Biol., 1999 Aug , 11, 503-8

PubMed link:

Inwardly rectifying potassium (Kir) channels regulate the resting membrane potential of the cell and thereby modulate the electrical activity of cardiac and neuronal cells, insulin secretion and epithelial K(+) transport. Considerable progress in understanding the molecular structure of Kir channels and the way in which they are regulated by extracellular and intracellular modulators has been made during the past year.