cacna2d1
Description: calcium channel, voltage-dependent, alpha2/delta subunit 1 Gene: Cacna2d1 Synonyms: cacna2d1
Introduction
Gene
Transcript
Acc No | Sequence | Length | Source | |
---|---|---|---|---|
NM_001110847 | n/A | n/A | NCBI | |
NM_001110848 | n/A | n/A | NCBI | |
NM_012919 | n/A | n/A | NCBI | |
NM_009784 | n/A | n/A | NCBI | |
NM_001110843 | n/A | n/A | NCBI | |
NM_001110844 | n/A | n/A | NCBI | |
NM_001110845 | n/A | n/A | NCBI | |
NM_001110846 | n/A | n/A | NCBI | |
NM_000722 | n/A | n/A | NCBI |
Ontology
Accession | Name | Definition | Evidence | |||||||
---|---|---|---|---|---|---|---|---|---|---|
GO:0016529 | sarcoplasmic reticulum | A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage. | IEA | |||||||
GO:0016020 | membrane | Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. | IEA | |||||||
GO:0005891 | voltage-gated calcium channel complex | A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential. | IMP | |||||||
GO:0030315 | T-tubule | Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane. | IEA | |||||||
GO:0016021 | integral to membrane | Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. | IEA | |||||||
GO:0005891 | voltage-gated calcium channel complex | A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential. | IEA |
Interaction
Protein
Structure
Distribution
Expression
Functional
Kinetics
Model
References
Tuluc P
et al.
Computer modeling of siRNA knockdown effects indicates an essential role of the Ca2+ channel alpha2delta-1 subunit in cardiac excitation-contraction coupling.
Proc. Natl. Acad. Sci. U.S.A.,
2007
Jun
26
, 104 (11091-6).
Hatano S
et al.
Molecular and electrophysiological differences in the L-type Ca2+ channel of the atrium and ventricle of rat hearts.
Circ. J.,
2006
May
, 70 (610-4).
Credits
To cite this page: [Contributors] Channelpedia https://channelpedia.epfl.ch/ionchannels/100/ , accessed on [date]