Channelpedia

PubMed 9602108


Referenced in Channelpedia wiki pages of: none

Automatically associated channels: Kv1.4 , Kv3.1 , Kv4.1 , Kv4.2 , Kv4.3



Title: Arachidonic acid-sensitive A-currents and multiple Kv4 transcripts are expressed in chick ciliary ganglion neurons.

Authors: L Dryer, Z Xu, S E Dryer

Journal, date & volume: Brain Res., 1998 Apr 6 , 789, 162-6

PubMed link: http://www.ncbi.nlm.nih.gov/pubmed/9602108


Abstract
A-currents (IA) of chick ciliary ganglion (CG) neurons were blocked reversibly by arachidonic acid and a non-metabolizable analog of arachidonic acid, 5,8,11,14-eicosatetraynoic acid. Inhibition of IA by both lipids was observed in whole-cell recordings and in excised inside-out patches, suggesting that Kv4 (Shal) subunits contribute to functional IA channels in CG neurons. Consistent with this, Kv4.2 and Kv4.3 cDNAs were isolated by RT-PCR from chick CG neurons.